Effect Metformin on Superoxide Dismutase and Nuclear Factor Kappa Beta in Diabetes Patient with Tuberculosis Infection

Novita, Bernadette Dian (2015) Effect Metformin on Superoxide Dismutase and Nuclear Factor Kappa Beta in Diabetes Patient with Tuberculosis Infection. In: World Diabetes Congress, 30 November - 4 Desember 2015, Vancouver, Canada. (Unpublished)

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Abstract

Metformin (MET) has possibilities of utilizing as a combination drug with existing antibiotics for TB therapy and controlling the growth of drug-resistant Mycobacterium tuberculosis strains via production of mitochondrial reactive oxygen species and facilitates phagosome-lysosome fusion. MET whom given to type 2 DM newly TB co-infection patients were improved the SOD’s level and inhibited of NF-ĸβ activation. The clinical effect, especially smear reversion, during metformin applied with anti-tuberculosis and insulin in patients with type 2 DM newly TB co-infection were remain unknown, and this result contributes much to our understanding the use of MET in type 2 DM-TB co-infection management.

Item Type: Conference or Workshop Item (Poster)
Subjects: Medicine
Medicine > RM Therapeutics. Pharmacology
Divisions: Proceeding > Faculty of Medicine
Depositing User: Dr Bernadette Dian Novita Dewi
Date Deposited: 03 Apr 2018 08:19
Last Modified: 26 Apr 2018 08:23
URI: http://repository.wima.ac.id/id/eprint/14454

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