Perbandingan Distribusi Dan Pola Kepekaan Acinetobacter baumannii Terhadap Antimikroba Di RSUD Dr. Soetomo Surabaya Periode Januari–Maret 2015, April–Juni 2015, dan Januari–Maret 2016

Sutandhio, Silvia and Widodo, Agung Dwi Wahyu and Alimsardjono, Lindawati and Wasito, Eddy Bagus (2018) Perbandingan Distribusi Dan Pola Kepekaan Acinetobacter baumannii Terhadap Antimikroba Di RSUD Dr. Soetomo Surabaya Periode Januari–Maret 2015, April–Juni 2015, dan Januari–Maret 2016. Jurnal Widya Medika, 4 (1). pp. 18-23. ISSN 2338-0373

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Abstract

Acinetobacter baumannii is an environmental bacteria that can cause opportunistic infectionssuch as ventilator-associated pneumonia, burn wound infection, urinary tract infection, and sepsis in immunocompromised patients. A. baurnannii infections are troublesome because the bacteria resistance to many antimicrobial agents. Surveillance of distribution and sensitivity pattern of A. baumannii is best to be done frequently in hospitals. Venous blood as much as 10 milliliters was drawn aseptically and transferred into liquid medium Bactec@ to be sent to I Clinical Microbiology Laboratory of Dr. Soetonlo General and Teaching Hospital. Medium that showed bacterial growth was subcultured on Blood Agar Plate and MacConkey Agar, and I incubated for 18-24 hours in aerobic condition. Iu'entijication and susceptibility test were done with semi-automated system BD Phoenix, and interpreted based on Clinical and Laboratory Standards Institute 2015. A. baumannii collected on trimester January-March 2015 were 30 isolates, with 19 isolates being Multidrug Resistant (MDR) A. baumannii (63%) and 6 isolates Pandrug Resistant (PDR) A. baumannii (20%). Isolates fiom trimester April-June 2015 were 32 isolates, with 21 isolates being MDR A. baumannii (66%) and 2 isolates PDR A. baumannii (6%). Isolates from trimester January-March 2016 were 40 isolates, with 22 isolates being MDR A. baumannii (55%) and 2 isolates PDR A. baumannii (5%). A. baumannii mostly isolated from Intensive Care Unit, followed by Internal medicine ward, Pediatric ward, Surgery ward and Emergency Department. High sensitivity of A. baumannii on trimester January-March 2016 was to imipenem (50%), meropenem (50%), amikacin (53%), cotrimoxazole (53%), dan cefoperazone-sulbactam (55%).. MDR A. baumannii mostly isolated fiom ICU, which reflects high burden of antimicrobial use. At this moment, antimicrobial agents that can be used as empirical therapy for A. baumannii infection are imipenem, meropenem, amikacin, cotrimoxazole, and cefoperazone-sulbactam. The entire hospital member must implement the Infection Control andprevention and Antimicrobia1 Stewardship Program toprevent nosocomial infections by A. baumannii and the emergence of MDR A. baumannii.

Item Type: Article
Uncontrolled Keywords: Acinetobacter baumannii, blood, distribution, susceptibility patterns
Subjects: Medicine
Divisions: Journal Publication
Depositing User: F.X. Hadi
Date Deposited: 22 Oct 2018 04:34
Last Modified: 22 Oct 2018 04:34
URI: http://repository.wima.ac.id/id/eprint/16317

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