Distribusi Dan Pola Kepekaan Enterobacteriaceae dari Spesimen Urin Di RSUD DR. Soetomo Surabaya Periode Januari – Juni 2015

Sutandhio, Silvia and Alimsardjono, Lindawati and Lusida, Maria Inge (2015) Distribusi Dan Pola Kepekaan Enterobacteriaceae dari Spesimen Urin Di RSUD DR. Soetomo Surabaya Periode Januari – Juni 2015. Jurnal Widya Medika, 3 (1). pp. 1-8. ISSN 2338-0373

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Official URL: http://journal.wima.ac.id/index.php/JWM/article/vi...

Abstract

Objective: Urinary tract bacterial infection is commonly caused by Enterobacteriaceae. Ideally, every hospital should have their own germ map and bacterial sensitivity patterns to be used as a guide for empirical therapy and tool to monitor of multidrug-resistant bacteria. Urine culture results, which provide supporting data for diagnosis and selection of definitive antimicrobial therapy, can be used to achieve that purpose. Method: Urine specimens are cultured in primary media for isolation, and then identified by manual and semi-automatic system, i.e. BD Phoenix and Vitek 2, which have been confirmed with Clinical and Laboratory Standards Institute 2015. Result: As much as 57.2% of 1983 isolates were identified as Enterobacteriaceae, with specification as follows: 59.6%, 18.1%, 0.1%, 10.0%, and 3.8% for Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Enterobacter spp., and Proteus spp., respectively. Over 50% of Escherichia coli, Klebsiella pneumoniae,and Klebsiella oxytoca isolates were Extended-Spectrum Beta Lactamase (ESBL) producers. Conclusion: Enterobacteriaceae that were isolated commonly resistant to Ampicillin and 1st generation of Cephalosporin, but still sensitive to Carbapenems and Aminoglycosides. Carbapenems, which should be considered as one of the last antimicrobial agents to be chosen in multidrug-resistant Enterobacteriaceae infection cases, should only be prescribed if there were indications, to prevent the emergence of Carbapenem-resistant organisms.

Item Type: Article
Uncontrolled Keywords: Enterobacteriaceae, Urine, ESBL, Carbapenem
Subjects: Medicine
Divisions: Journal Publication
Depositing User: F.X. Hadi
Date Deposited: 13 Sep 2019 05:59
Last Modified: 27 Sep 2019 01:16
URI: http://repository.wima.ac.id/id/eprint/20104

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