Comparison of in vivo antidiabetes activity of snake fruit Kombucha, black tea Kombucha and metformin

Zubaidah, Elok and Afgani, Chairul Anam and Kalum, Umi and Srianta, Ignatius and Blanc, Philippe J (2019) Comparison of in vivo antidiabetes activity of snake fruit Kombucha, black tea Kombucha and metformin. Biocatalysis and Agricultural Biotechnology, 17. pp. 465-469. ISSN 1878-8181; Jurnal Internasional Bereputasi, Q2, SJR: 0,5

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Official URL: https://www.sciencedirect.com/science/article/pii/...

Abstract

The research compared antidiabetic activity of snake fruit Kombucha, black tea Kombucha and metformin in streptozotocin-induced diabetic rats. Snake fruit Kombucha, black tea Kombucha and metformin were orally administered to the diabetic rats daily during a 28-day experiment. Fasting plasma glucose (FPG) levels, superoxide dismutase (SOD) activities, malondialdehyde (MDA) levels and lipid profiles (total triglyceride, total cholesterol, LDL-cholesterol and HDL-cholesterol) of the blood plasma were investigated. Pancreas immunohistochemical study and β-cells quantification were also conducted. The products significantly (p < 0.05) reduced fasting plasma glucose levels (67–76%) and improved oxidative stress indices and lipid profiles. From immunohistochemical staining of pancreatic tissues, pancreatic β-cells were also improved in the diabetic rats by the products. The snake fruit Kombucha compared with the metformin but better than the black tea Kombucha as a diabetes therapy agent.

Item Type: Article
Additional Information: Jurnal Internasional Bereputasi, Q2, SJR: 0,5
Uncontrolled Keywords: Diabetes Mellitus Fermentation Kombucha Pancreatic β-cells Fasting plasma glucose
Subjects: Agriculture and Food Technology
Divisions: Journal Publication
Depositing User: F.X. Hadi
Date Deposited: 26 Nov 2019 04:25
Last Modified: 20 Dec 2019 07:36
URI: http://repository.wima.ac.id/id/eprint/20185

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