The Effect Of Cinnamomum Burmannii Water Extraction Against Staphylococcus Aureus, Enterobacter SPP., Pseudomonas Aeruginosa, And Candida Albicans: In Vitro Study

Novita, Bernadette Dian and Sutandhio, Silvia (2019) The Effect Of Cinnamomum Burmannii Water Extraction Against Staphylococcus Aureus, Enterobacter SPP., Pseudomonas Aeruginosa, And Candida Albicans: In Vitro Study. Folia Medica Indonesiana, 55 (4). ISSN 2355-8393

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Official URL: https://e-journal.unair.ac.id/FMI/article/view/173...

Abstract

Indonesian cinnamon (Cinnamomum burmannii) is a native plant of Indonesia that has a lot of potential. The most consumed part is the bark. This study aims to examine the antimicrobial effect of Cinnamomum burmannii bark extract on various types of pathogenic microbes, namely Staphylococcus aureus, Enterobacter spp., Pseudomonas aeruginosa, and Candida albicans. An experimental study using a water extract (infusion) of Cinnamomum burmannii bark and a microbial test obtained from the Faculty of Pharmacy, Widya Mandala Catholic University, Surabaya. The antimicrobial effect test was carried out by the microdilution method in 96-well-microplate to determine the Minimum Inhibitory Level (MIC) and implantation on solid media to determine the Minimum Kill Rate (KBM). The MIC and KBM against Staphylococcus aureus were 625-1,250 ppm and 1,250-2,500 ppm, respectively. MIC and KBM for Enterobacter spp., Pseudomonas aeruginosa, and Candida albicans were not found at the highest concentrations tested at 10,000 ppm. Cinnamomum burmannii extract can be used as a potential ingredient with antimicrobial effects, especially against Gram-positive bacteria. Future studies should pay attention to the quality of simplicia, particle size, and the most effective extraction methods extracting antimicrobial substances from simplicia.

Item Type: Article
Contributors:
ContributionContributorsNIDN / NIDKEmail
ResearcherUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
ResearcherUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Subjects: Medicine > RM Therapeutics. Pharmacology
Divisions: Faculty of Medicine
Depositing User: Dr Bernadette Dian Novita Dewi
Date Deposited: 05 May 2020 07:52
Last Modified: 05 May 2020 07:52
URI: http://repository.wima.ac.id/id/eprint/21780

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