Wijaya, Sumi, Nee, Ting Kang, Jin, Khoo Teng, Din, Wardah Mustafa and Wiart, Christophe (2011) Antioxidant, Anti-Inflammatory, Cytotoxicity and Cytoprotection Activities of Crassocephalum Crepidioides (Benth.) S. Moore. Extracts and Its Phytochemical Composition. European Journal of Scientific Research, 67 (1). pp. 1-10. ISSN 1450-216X, Journal Internasional Terindek di SJR
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Abstract
The hexane, ethyl acetate, ethanol and water extracts of Crassocephalum crepidioides (Benth.) S. Moore. were assessed for their antioxidant, anti-inflammatory, cytoxicity and cytoprotective activities. The ethanol extract displayed profound antioxidant activities and inhibited the enzymatic activity of 5-lipoxygenase (5-LOX). The ethanol extract of Crassocephalum crepidioides (Benth.) S. Moore. at a concentration of 100 μg/ml, was non-toxic against MRC-5 and HepG2 cell lines. At the concentration of 25 μg/ml it gave a percentage of cytoprotection with the value of 69.47%. Phytochemical analysis of the ethanol extract revealed the presence of phenols and flavonoids with 422.22 gallic acid equivalent (mg/g) and 3.46 quercetin equivalent (mg/g). Phenolic compounds and flavonoids impart to Crassocephalum crepidioides (Benth.) S. Moore. its biological properties.
Item Type: | Article |
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Uncontrolled Keywords: | -- |
Subjects: | Pharmacy |
Divisions: | Journal Publication |
Depositing User: | F.X. Hadi |
Date Deposited: | 09 Oct 2019 07:32 |
Last Modified: | 16 Aug 2021 02:58 |
URI: | http://repository.ukwms.ac.id/id/eprint/20125 |
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