A Review of Gum Hydrocolloid Polyelectrolyte Complexes (PEC) for Biomedical Applications: Their Properties and Drug Delivery Studies

Putro, Jindrayani Nyoo, Lunardi, Valentino Bervia, Soetaredjo, Felycia Edi, Yuliana, Maria, Santoso, Shella Permatasari, Wenten, I Gede and Ismadji, Suryadi (2021) A Review of Gum Hydrocolloid Polyelectrolyte Complexes (PEC) for Biomedical Applications: Their Properties and Drug Delivery Studies. A Review of Gum Hydrocolloid Polyelectrolyte Complexes (PEC) for Biomedical Applications: Their Properties and Drug Delivery Studies, 9 (1796). pp. 1-29. ISSN 22279717, Jurnal Internasional Bereputasi SJR(2020): 0.41, Q2, H-Index: 28

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Abstract

The utilization of natural gum polysaccharides as the vehicle for drug delivery systems and other biomedical applications has increased in recent decades. Their biocompatibility, biodegradability, and price are much cheaper than other materials. It is also renewable and available in massive amounts, which are the main reasons for its use in pharmaceutical applications. Gum can be easily functionalized with other natural polymers to enhance their applications. Various aspects of the utilization of natural gums in the forms of polyelectrolyte complexes (PECs) for drug delivery systems are discussed in this review. The application of different mathematical models were used to represent the drug release mechanisms from PECs; these models include a zero-order equation, first-order equation, Higuchi, simplified Higuchi, Korsmeyer–Peppas, and Peppas–Sahlin.

Item Type: Article
Additional Information: Jurnal Internasional Bereputasi SJR(2020): 0.41, Q2, H-Index: 28
Uncontrolled Keywords: gum polysaccharides; drug delivery; polyelectrolyte complexes; hydrocolloid
Subjects: Engineering > Chemical Engineering
Divisions: Journal Publication
Depositing User: F.X. Hadi
Date Deposited: 19 Nov 2021 03:06
Last Modified: 03 Aug 2022 01:43
URI: http://repository.ukwms.ac.id/id/eprint/27457

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